Whether or androgen agonists should be used to treat male patients who test positive for androgen receptors has not yet been determined 2. The patient should be informed about the high morbidity of the surgical intervention. Among women sites which are frequently involved include the vulva, the vagina, the groin, the buttocks and the peritoneum, but it has also been described in the oral cavity, the uterus, the cervix, the bladder and the pararenal space 4, 7, View at Google Scholar I. This condition which highlights the need to consider AA may be potentially malignant in some cases [ 4 ]. Case Reports in Medicine.
Recurrence has been developed mostly within the first 3 years [ 14 ]. Morphologically, the tumor was composed of spindled and stellate-shaped cells with ill-defined cytoplasm intermingled with collagen fibers and thin vessels in a myxoid background. On physical examination, she had a left groin incision scar. Typically angiomyxoma is a slow growing locally infiltrative lesion, but it is not invasive or capped 10, This side was resected and primarily repaired.
Case Reports in Surgery
However, it may be detected even after postoperative 15 years [ 11 ]. Their mesenchymal neoplastic cells are hyperchromatic with dense homogeneous chromatin. It is important to differentiate angiomyxoma from angiomyofibroblastoma of the vulva which shares histogenic features with angiokyxoma.
Respecting this view, we believe that it is not compatible with the oncological principles. During examination exceptional cases have presented hemorrhaging or necrosing tissue, while other cases are encapsulated and well circumscribed It is likely due to the loose myxoid matrix and high-water content of AA [ 8 ]. The tumor is distinguished from other lesions by these histopathologic features.
Digital examination of the rectum was normal. This is an open access article distributed under literaturd Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Administered prior to surgery it reduces tumor extension and thus reduces resulting morbidity 2, 8. Presacral lesion after extraction.
This established the diagnosis of a presacral tumor Figure 1. Incidence and reports of the disease have been increasing each year Aggressive angiomyxoma AA is an uncommon mesenchymal tumor that is mostly derived from the female pelvic and perineal regions.
Zuur and The Language Workshop Received: Complete excision of the lesion with wide surgical margins is the treatment of choice. They are even more exotic in men, with very few cases reported in the literature. Case Report and Literature Review. The tumor was completely excised by sharp and blunt dissection Figure 2.
Archive ouverte HAL – Aggressive angiomyxoma: A case series and literature review
Vulva was examined macroscopically because the patient was virgin. Whether or androgen agonists should be used to treat aggrfssive patients who test positive for androgen receptors has not yet been determined 2.
There have been no reports of metastasis among men to date Rev Med Hosp Gen Mex ; 70 2: The patient recovered uneventfully and was discharged from the hospital on postoperative day 8. Embolization of the tumor has been reported as an alternative approach; however, it remains insufficient due to the extensive vascular network of the tumor. The female to male ratio is approximately 6. It is notable that preoperative imaging has a crucial importance in the diagnosis of AA.
According to the histopathological and immunohistochemical findings, the case was interpreted as intra-abdominal aggressive angiomyxoma. The female-to-male ratio has been reported as 6.
Clinical case report and literature review Juan Fernando Medina R. Intravenous pyelograms, marrow scintigraphy, barium enemas and pelvic angiography have also been used to assess the extent of the lesion before surgery 6.
Another important characteristic is that these lesions form masses that displace rather than infiltrate adjacent structures 3, 9. While its age distribution has a wide range, it occurs most frequently between ages 18 and 63 with peak incidence during the reproductive years from the second to fourth decades of life. This side was resected and primarily repaired. The tumor was invading adjacent soft tissue including adipose tissue, muscles, and nerves.
A total colonoscopy found nothing else of note and ruled out other lesions as explanations of the single episode of self-limiting rectal bleeding.