This showed that the positive expression was more common in papillary as compared to follicular carcinomas. Pak J Med Sci. Am J Clin Pathol. FNAC was highly sensitive in diagnosing papillary carcinoma of thyroid with Fine needle aspiration cytology of thyroid nodules at Kenyatta National Hospital, Nairobi. After taking the consent of the patient, FNAC was done and two smears and a cellblock were prepared. Significant difference was not observed between original and review cases in terms of sensitivity, specificity, PPV, NPV and accuracy.
Il Giornale di chirurgia. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Am J Clin Pathol. Maharajan r Ch, Rao H. Galectin-3, plays a pivotal role in processes like cell proliferation, cell-cell interaction, and cell-matrix adhesion mainly via binding to glycoproteins.
Correlation of fine needle aspiration and final histopathology in thyroid disease: Significant difference was not observed between original and review cases in terms of sensitivity, specificity, PPV, NPV and accuracy.
Htyroid air-dried smears were stained with modified wright stain Diff-Quick and the smears fixed with absolute ethyl alcohol were stained with Papanicolaou stain. Pak J Med Sci. The many pathologists involved in reporting histopathology could have over-estimated or under-estimated malignancy rate random error.
In our study 15 cases were found to be malignant on histopathological examination 12 papillary carcinoma and 3 hurthle cell lesions.
Objectives To estimate the sensitivity and specificity of FNAC in detecting malignancy for thyroid disease using histopathology as the gold standard. Ethical consideration Before the start of this study, ethical clearance was obtained from the Institutional Review Board of Makerere University College of Thdsis Sciences. Diagnostic accuracy of fine needle aspiration cytology in thyroid lesions: Commonest malignancy detected was papillary carcinoma in 12 patients.
Journal List Afr Health Sci v.
However, no case of medullary or anaplastic carcinoma was diagnosed in our study Fig. Yoon, Han-Seung; Fitzgerald, Peter.
Journal of Thyroid Research
Majority of the goiters were benign Results A total of 75 patients with solitary thyroid nodule were identified: All the authors contributed equally and agreed to the final manuscript. Fine-needle aspiration of the thyroid an overview. Of the histologically confirmed neoplastic cases, were correctly identified as a neoplasm on FNAC and recommended for surgery.
All the patients presented with solitary thyroid nodule.
Purpose of the present study was to correlate the fine needle aspiration cytology findings with histopathology tgesis excised specimens. Galectin-3 and Ki expression in multiglandular parathyroid lesions. Application of immunohistochemistry to thyroid neoplasms.
The negative predictive value in this study was The proportion of patients with malignancy was Dissertation submitted in partial fulfillment for the award of degree of master of medicine in surgery of Makerere University. Two slides were air dried where as the other two were fixed immediately by immersion into absolute ethyl- alcohol.
The Accuracy of Manual Fine Needle Aspiration Cytology in the Evaluation of Thyroid Cancer
Aim The objective of this study is to determine the accuracy of manual FNAC for the diagnosis of histologically proven thyroid malignancy in a community pathology practice over a year period. This item is not available in full-text via OUR Archive.
The purpose of this study was to estimate the sensitivity and specificity of FNAC in detecting malignancy for thyroid disease using histopathology of excised specimen as a gold standard and cnac describe histopathological diagnoses of thyroid disease in patients following thyroidectomy. O Box Gulu – Uganda. The retrospective arm involved retrieving patients’ records cytological and histopathological reports from the pathology department of Makerere University College of Health Sciences MakCHS that had undergone thyroidectomy from January to December htesis the other arm involved prospective recruitment of patients from January to April Of the malignant histopathology, majority All cases of histologically confirmed thyroid abnormalities for the Otago and Southland regions were identified for the period of 15 years from The sensitivity for diagnosing malignancy on FNAC was RM developed the concept, participated in data collection and manuscript writing, PKO participated in data collection, analysis, manuscript writing, JOF and DW reviewed the concept, data analysis and manuscript.